By Marina Zhang

Epoch Times

Why do some people report adverse events after COVID-19 vaccinations while some do not?

This question is central to the controversy of COVID-19 vaccine adverse events.

Doctors have identified several factors that contribute to an increased risk of spike protein-induced disease, specifically, post COVID-19 vaccine injury.

Dr. Paul Marik, Front Line COVID-19 Critical Care Alliance (FLCCC) co-founder, said at an FLCCC conference on Oct. 15 that long COVID and injury from the COVID-19 vaccines share many overlaps in their symptoms and mechanisms.

Both diseases are systemic, affecting multiple organs and tissues, and are both driven by a high load of spike protein accumulated in these organs and tissues.

These spike proteins trigger inflammation, mitochondrial dysfunction and autoimmunity.

However, not everyone will experience these symptoms.

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Spike protein exposure increases risk, severity

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There is a dose response with the vaccine, such that the greater the number of vaccine doses, the higher the risk of spike protein injury.

“The more the patients are exposed to spike [proteins], the more severe the disease,” said Marik.

Both long COVID and injury from COVID-19 vaccines are driven by prolonged exposure to spike proteins through infection and vaccination respectively, he explained.

Dr. Flavio Cadegianni hypothesized that receiving COVID-19 vaccines after having had COVID-19 increases one’s risk of spike protein injury.

This is because vaccines likely trigger a higher amount of spike protein load in the bloodstream than a common COVID-19 infection.

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Spike proteins from vaccination have been observed to be present even at nine months following vaccination, so subsequent shots and boosters could lead to more spike protein production, increased inflammatory complexes formation and higher risk of symptom onset.

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Varied loads in vaccines

Not all vaccine vials are made the same.

How Bad is My Batch is a website that compiles data on adverse events from the Vaccine Adverse Event Reporting System (VAERS) on COVID-19 vaccination.

By separating each adverse event into its corresponding vaccine batch, the website has shown that some vials were made different from others, as they are associated with a greater number of adverse events, deaths and disabilities.

This could be due to impurities in the vaccines.

Leaked emails from staff in the European Medicines Agency showed that the agency only asked for 50% mRNA integrity in their Pfizer vaccinations.

However, potential issues could also be due to the dosage; some vials may have a higher mRNA or DNA spike protein content than others.

Currently, doctors have no way to verify what is in the vials.

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Genetic factors

“There’s a genetic predisposition,” said Marik. “If someone in the family is vaccine injured, it is very common that the brothers of that individual … [will also become] vaccine injured so there are genetic factors which we don’t understand.”

Marik has observed that certain genetic mutations may also put them at a greater risk of COVID-19 vaccine injury.

This included individuals with a methylenetetrahydrofolate reductase (MTHFR) gene mutation and those with Ehlers-Danlos type syndromes.

Around 40% of people in the U.S. carry or are affected by the MTHFR mutation. It is an enzyme responsible for transforming folate (vitamin B9) into its active form.

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Underlying chronic diseases and immune deficiencies

Metabolic diseases, especially high blood pressure and type 2 diabetes, have been associated with severe symptoms in COVID-19 infections and vaccination.

Dr. Aseem Malhotra, a renowned cardiologist, wrote in his paper that even “a single high blood glucose reading in non-diabetics admitted to hospital [for COVID-19] has been shown to be associated with worse outcomes.”

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Spike proteins are also highly autoimmune, meaning that it is able to trigger the immune system to mount attacks against self-tissues.

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Deficiencies in folate, cobalamin (vitamin B12) and vitamin D have been associated with an elevated risk of COVID-19 infection.

A pre-print study authored by UK researchers funded by the National Health Service found that supplementation in vitamin D and vitamin B12 relieved neurological symptoms caused by COVID-19 vaccination.

Vitamin D is anti-inflammatory and can boost immune action, while vitamin B12 is critical for neural health as it helps to produce myeline, which is a fatty coat wrapped around neurons, that helps protect neurons against scarring and improves neural messaging.

“Vaccines, including the COVID-19 vaccines, are known to cause severe and/or chronic neurological reactions in rare cases. We support screening for vitamin B12 deficiency prior to vaccination in high-risk groups,” wrote the study authors.

Folate deficiencies have also been observed in patients hospitalized with COVID-19. The vitamin plays a role in the formation of DNA and RNA for cellular protein.

Age and sex

Marik said that women are generally more at risk of injury from COVID-19 vaccination.

He based this statement on the results from a survey conducted by React19, a website that provides advice on vaccine injuries and early treatment.

There were 508 patients suffering from post-vaccination injury evaluated in October 2021 as part of the questionnaire.

The survey found that 81% of people reporting vaccine injury were females. Between the two sexes, patients aged between 30 to 50 were the most prevalent.

Data from VAERS also showed that women constituted around 65% of the adverse event reports; 41% of these reports came from women aged 18 to 49 at the time of the report

Women in the 50 to 59 age bracket and the 65 to 79 age bracket also constituted a large fraction of the adverse event reports, taking up almost 35% of all reports in females.

Spike proteins trigger inflammation through many pathways.

One pathway is through binding to ACE2 receptors on cell surfaces. This receptor is important for reducing inflammation, and a reduction of ACE2 through spike protein interaction thus increases inflammation.

Though ACE2 receptors are found across many organs, studies show that it is particularly abundant in the ovaries and the eggs.

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Via https://childrenshealthdefense.org/defender/covid-vaccine-injury-risk-et/