Breast cancer risk linked to hormone therapy can persist for years

Specifically, the research suggests that the estimated incidence of breast cancer at ages 50 to 69 was tied to an increased risk — from 6.3% of women who never used hormone replacement therapy to 8.3% of those who used the therapy daily for five years. That’s an increase of about one extra cancer case in every 50 users of the therapy, according to the research.

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(CNN) – Certain hormone replacement therapies have long been tied to an increased risk of breast cancer. Now, new research suggests that in some cases, that risk can persist for more than a decade.
The research, published in the journal The Lancet on Thursday, found that risks increased steadily the longer the hormone replacement therapy was used, and were greater for estrogen-progestogen hormone therapies than for estrogen-only hormone therapy. Every type of hormone replacement therapy, except for vaginal estrogens, was associated with excess breast cancer risks.

The menopausal transition most often begins between ages 45 and 55, causing symptoms to appear due to changes in the body’s production of the sex hormones estrogen and progesterone. Sometimes women take hormone replacement therapy, also called HRT or menopausal hormone therapy, to help relieve symptoms of menopause, such as hot flashes, night sweats, pain during sex and vaginal dryness. Those symptoms can be…

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