By Dr. Mercola
Via Justice Truth News
STORY AT-A-GLANCE
- Recent research suggests melatonin may be an important adjunct to COVID-19 treatment
- Patients hospitalized with pneumonia and COVID-19 who were given high-dose melatonin as an adjunct therapy to standard of care improved within four to five days, and all survived
- Melatonin inhibits the cytokine storm associated with critical SARS-CoV-2 infection. It also inhibits sepsis (blood poisoning), associated with an overactive immune response
- Melatonin helps prevent mitochondrial impairment, energy failure and apoptosis (programmed cell death) in mitochondria damaged by oxidation
- Melatonin also helps regulate and improve risk factors for severe COVID-19, such as high blood pressure, insulin resistance and diabetes
This article was previously published October 19, 2020, and has been updated with new information.
According to a June 2020 research paper,1 melatonin2,3 may be an important adjunct to COVID-19 treatment. Incidentally, while not emphasized, melatonin is an optional addition to the highly effective MATH+ protocol promoted by the Front Line COVID-19 Critical Care Working Group (FLCCC).4
President Trump’s COVID-19 treatment5 was also said to include melatonin supplementation. The authors note that melatonin attenuates several pathological features of the illness, including excessive inflammation, oxidation and an exaggerated immune response resulting in a cytokine storm and acute lung injury (ALI), acute respiratory distress syndrome (ARDS) and, potentially, death.
“Melatonin, a well-known anti-inflammatory and anti-oxidative molecule, is protective against ALI/ARDS caused by viral and other pathogens,” the researchers state,6 adding:
“Melatonin is effective in critical care patients by reducing vessel permeability, anxiety, sedation use, and improving sleeping quality, which might also be beneficial for better clinical outcomes for COVID-19 patients.
Notably, melatonin has a high safety profile. There is significant data showing that melatonin limits virus-related diseases and would also likely be beneficial in COVID-19 patients.”
One of the things that makes melatonin so effective is that it doesn’t just act as an antioxidant in and of itself; it also interacts with your body’s innate antioxidant system where it recharges glutathione.7
High-Dose Melatonin to Combat COVID-19
A recent case series8 published in the journal Melatonin Research details how patients hospitalized with COVID-19 pneumonia who were given high-dose melatonin as an adjunct therapy to standard of care all improved within four to five days, and all survived.
On average, those given melatonin were discharged from the hospital after 7.3 days, compared to 13 days for those who did not get melatonin. This is far better than the expensive treatment remdesivir, which costs over $3,000 and doesn’t produce anywhere near this improvement.
However, the patients were given very large doses of melatonin, 36 mg to 72 mg per day in four divided doses. When used for sleep, you’d typically start with a dose of 0.25 mg and work your way up as needed.
Dr. Richard Neel and colleagues at Little Alsace and Uvalde Urgent Care clinics in Texas are also using high-dose melatonin in combination with vitamin C and vitamin D, and had as of the last week of July 2020 successfully treated more than 400 patients.9
Because of melatonin’s potent antioxidant and anti-inflammatory activities, it would normally reduce the highly proinflammatory cytokine storm and neutralize the generated free radicals thereby preserving cellular integrity and preventing lung damage. ~ Medical Drug Discoveries June 2020.